Lactic acidosis complicating treatment of ketosis of labour.

744 22 March 1969 Lactic Acidosis in Diabetes

S ummary: Lactic acidosis is occasionally responsible for metabolic acidosis in diabetics. It may occur in the presence of normal blood levels of the ketone bodies, and such cases are often described as having "non-ketotic diabetic acidosis." Lactic acid may contribute to the metabolic acidosis in patients with true diabetic ketoacidosis, but the blood lactate concentrations in these patients a...

An unusual case of metformin associated lactic acidosis.

Metformin Associated Lactic Acidosis (MALA) is a rare, but serious complications of Type 2 diabetes mellitus treatment with a mortality rate of around 50%. It most commonly occurs in the setting of hepatic, cardiac or renal insufficiency. We report the case of an elderly female with MALA and concomitant starvation ketosis in the absence of any known risk factor, who went undiagnosed for a perio...

False positive ethylene glycol determination by spectrophotometry in the presence of severe lactic acidosis and ketosis.

Acute Metabolic Complications in Diabetes

The acute metabolic complications of diabetes consist of diabetic ketoacidosis (DKA), hyperosmolar non-ketotic coma (HNC), lactic acidosis (LA), and hypoglycemia. DKA and HNC are related to insulin deficiency. Hypoglycemia results from the treatment of diabetes, either with oral agents or insulin. Although hypoglycemia may occur in conjunction with oral hypoglycemic therapy, it is more common i...

Sleep-disordered breathing in middle-aged adults predicts no significantly higher rates of traffic violations.

the study by Lever and Jaspan8 that was cited by Dr. Rosival is different from his. These authors do not seem to support the idea of giving sodium bicarbonate to patients with diabetic ketoacidosis. In their retrospective analysis of 95 episodes of severe diabetic ketoacidosis, they concluded that sodium bicarbonate might not confer any special benefits in the treatment of diabetic ketoacidosis...